Publications

Recent publications (2011-2017)

2017

  • Wieczorek, R., Adamala, K., Gasperi, T., Polticelli, F., Stano, P. (2017) Small and Random Peptides: An Unexplored Reservoir of Potentially Functional Primitive Organocatalysts. The Case of Seryl-Histidine. Life (Basel) 7, E19.
  • Di Muzio, E., Toti, D., Polticelli, F. (2017) DockingApp: a user friendly interface for facilitated docking simulations with AutoDock Vina. J Comput Aided Mol Des. 31, 213-218.
  • Sinibaldi, F., Milazzo, L., Howes, B.D., Piro, M.C., Fiorucci, L., Polticelli, F., Ascenzi, P., Coletta, M., Smulevich, G., Santucci, R. (2017) The key role played by charge in the interaction of cytochrome c with cardiolipin. J. Biol. Inorg. Chem. 22,19-29.
  • Zobnina, V., Lambreva, M.D., Rea, G., Campi, G., Antonacci, A., Scognamiglio, V., Giardi, M.T., Polticelli, F. (2017) The plastoquinol-plastoquinone exchange mechanism in photosystem II: insight from molecular dynamics simulations. Photosynth. Res. 131, 15-30.

2016

  • Tundo, G.R., Di Muzio, E., Ciaccio, C., Sbardella, D., Di Pierro, D., Polticelli, F., Coletta, M., Marini, S.(2016) Multiple allosteric sites are involved in the modulation of insulin-degrading-enzyme activity by somatostatin. FEBS J. 283, 3755-3770.
  • Tortosa, V., Di Patti, M.C.B., Musci, G., Polticelli, F. (2016) The human iron exporter ferroportin. Insight into the transport mechanism by molecular modeling. Bio-Algorithms and Med-Systems 12, 1-7.
  • Centola, F., Polticelli, F. (2016) Molecular models of human visual pigments: Insight into the atomic bases of spectral tuning. Bio-Algorithms and Med-Systems 12, 141-146.
  • Rusconi, F., Ceriotti, P., Miragoli, M., Carullo, P., Salvarani, N., Rocchetti, M., Di Pasquale, E., Rossi, S., Tessari, M., Caprari, S., Cazade, M., Kunderfranco, P., Chemin, J., Bang, M.L., Polticelli, F., Zaza, A., Faggian, G., Condorelli, G., Catalucci, D. (2016) Peptidomimetic Targeting of Cavβ2 Overcomes Dysregulation of the L-Type Calcium Channel Density and Recovers Cardiac Function. Circulation 134, 534-546.
  • Cervelli, M., Leonetti, A., Cervoni, L., Ohkubo, S., Xhani, M., Stano, P., Federico, R., Polticelli, F., Mariottini, P., Agostinelli, E. (2016) Stability of spermine oxidase to thermal and chemical denaturation: comparison with bovine serum amine oxidase. Amino Acids 48, 2283-2291.
  • Pesiri, V., Di Muzio, E., Polticelli, F., Acconcia, F. (2016) Selective binding of estrogen receptor α to ubiquitin chains. IUBMB Life 68, 569-577.
  • Di Muzio, E., Polticelli, F., di Masi, A., Fanali, G., Fasano, M., Ascenzi, P. (2016) All-trans-retinoic acid and retinol binding to the FA1 site of human serum albumin competitively inhibits heme-Fe(III) association. Arch. Biochem. Biophys. 590, 56-63.
  • Pennisi, R., Salvi, D., Brandi, V., Angelini, R., Ascenzi, P., Polticelli, F. (2016) Molecular Evolution of Alternative Oxidase Proteins: A Phylogenetic and Structure Modeling Approach. J. Mol. Evol. 82, 207-218.
  • De Simone, G., Ascenzi, P., Polticelli, F. (2016) Nitrobindin: An Ubiquitous Family of All β-Barrel Heme-proteins. IUBMB Life 68, 423-428.
  • Traversi, G., Fiore, M., Leone, S., Basso, E., Di Muzio, E., Polticelli, F., Degrassi, F., Cozzi, R. (2016) Resveratrol and its methoxy-derivatives as modulators of DNA damage induced by ionising radiation. Mutagenesis 31, 433-441.
  • Di Muzio, E., Polticelli, F., di Masi, A., Fanali, G., Fasano, M., Ascenzi, P. (2016) All-trans-retinoic acid and retinol binding to the FA1 site of human serum albumin competitively inhibits heme-Fe(III) association. Arch. Biochem. Biophys. 590, 56-63.

2015

  • Polticelli, F., Zobnina, V., Ciaccio, C., de Sanctis, G., Ascenzi, P., Coletta, M. (2015) Enhanced heme accessibility in horse heart mini-myoglobin: Insights from molecular modelling and reactivity studies. Arch. Biochem. Biophys. 585:1-9.
  • Leboffe, L., Angelini, R., Menegatti, E., Polticelli, F., Ascenzi, P. (2015) Different disulfide bridge connectivity drives alternative folds in highly homologous Brassicaceae trypsin inhibitors. IUBMB Life. 67, 966-970.
  • Bonaccorsi di Patti, M.C., Polticelli, F., Tortosa, V., Furbetta, P.A., Musci, G.(2015) A bacterial homologue of the human iron exporter ferroportin. FEBS Lett. 589, 3829-3835.
  • Polticelli, F., Zobnina, V., Ciaccio, C., de Sanctis, G., Ascenzi, P., Coletta, M. (2015) Enhanced heme accessibility in horse heart mini-myoglobin: Insights from molecular modelling and reactivity studies. Arch. Biochem. Biophys. 585, 1-9.
  • Viet Hung, L., Caprari, S., Bizai, M., Toti, D., Polticelli, F. (2015) LIBRA: LIgand Binding site Recognition Application. Bioinformatics 31, 4020-4022.
  • Ciaccio, C., Oca�a-Calahorro, F., Droghetti, E., Tundo, G.R., Sanz-Luque, E., Polticelli, F., Visca, P., Smulevich, G., Ascenzi, P., Coletta, M. (2015) Functional and Spectroscopic Characterization of Chlamydomonas reinhardtii Truncated Hemoglobins. PLoS One 10, e0125005.
  • Ascenzi, P., Coletta, M., Wilson, M.T., Fiorucci, L., Marino, M., Polticelli, F., Sinibaldi, F., Santucci, R. (2015) Cardiolipin-cytochrome c complex: Switching cytochrome c from an electron-transfer shuttle to a myoglobin- and a peroxidase-like heme-protein. IUBMB Life 67, 98-109.
  • Cervelli, M., Polticelli, F., Angelucci, E., Di Muzio, E., Stano, P., Mariottini, P. (2015) Pacific oyster polyamine oxidase: a protein missing link in invertebrate evolution. Amino Acids 47, 949-961.

2014

  • Di Muzio, E., Polticelli, F., Trezza, V., Fanali, G., Fasano, M., Ascenzi, P. (2014) Imatinib binding to human serum albumin modulates heme association and reactivity. Arch. Biochem. Biophys. 560, 100-112.
  • Ascenzi, P., Marino, M., Polticelli, F., Santucci, R., Coletta, M. (2014) Cardiolipin modulates allosterically the nitrite reductase activity of horse heart cytochrome c. J. Biol. Inorg. Chem. 19, 1195-1201.
  • Musci, G., Polticelli, F., Bonaccorsi di Patti, M.C. (2014) Ceruloplasmin-ferroportin system of iron traffic in vertebrates. World J. Biol. Chem. 5, 204-215.
  • Cervelli, M., Angelucci, E., Stano, P., Leboffe, L., Federico, R., Antonini, G., Mariottini, P., Polticelli, F. (2014) The Glu216/Ser218 pocket is a major determinant of spermine oxidase substrate specificity. Biochem. J. 461, 453-459.
  • Bonaccorsi di Patti, M.C., Polticelli, F., Cece, G., Cutone, A., Felici, F., Persichini, T., Musci, G. (2014) A structural model of human ferroportin and of its iron binding site. FEBS J. 281, 2851-2860.
  • Santucci, R., Sinibaldi, F., Polticelli, F., Fiorucci, L. (2014) Role of Cardiolipin in Mitochondrial Diseases and Apoptosis. Curr. Med. Chem. 21, 2702-2714.
  • Lambreva, M.D., Russo, D., Polticelli, F., Scognamiglio, V., Antonacci, A., Zobnina, V., Campi, G., Rea, G. (2014) Structure/Function/Dynamics of Photosystem II Plastoquinone Binding Sites. Curr. Protein. Pept. Sci. 15, 285-295.
  • Caprari, S., Toti, D., Viet Hung, L., Di Stefano, M., Polticelli, F. (2014) ASSIST: a fast versatile local structural comparison tool. Bioinformatics 30, 1022-1024.
  • Scribano, D., Petrucca, A., Pompili, M., Ambrosi, C., Bruni, E., Zabaglia, C., Prosseda, G., Nencioni, L., Casalino, M., Polticelli F., Nicoletti, M. (2014) Polar Localization of PhoN2, a Periplasmic Virulence-Associated Factor of Shigella flexneri, Is Required for Proper IcsA Exposition at the Old Bacterial Pole. PLoS ONE 9, e90230.

2013

  • Cervelli, M., Salvi, D., Polticelli, F., Mariottini, P. (2013) Structure-function relationships in the evolutionary framework of spermine oxidase. J. Mol. Evol. 76, 365-370.
  • Scognamiglio, V., Stano, P., Polticelli, F., Antonacci, A., Dimova Lambreva, M., Pochetti, G., Giardi, M.T., Rea, G. (2013) Design and biophysical characterization of atrazine-sensing peptides mimicking the Chlamydomonas reinhardtii plastoquinone binding niche. Phys. Chem. Chem. Phys. 15, 13108-13115.
  • Sinibaldi, F., Howes, B.D., Droghetti, E., Polticelli, F., Piro, M.C., Di Pierro, D., Fiorucci, L., Coletta, M., Smulevich, G., Santucci, R. (2013) Role of lysines in cytochrome c - cardiolipin interaction. Biochemistry 52, 4578-4588.
  • Ascenzi, P., Marino, M., Polticelli, F., Coletta, M., Gioia, M., Marini, S., Pesce, A., Nardini, M., Bolognesi, M., Reeder, B.J., Wilson, MT. (2013) Non-covalent and covalent modifications modulate the reactivity of monomeric mammalian globins. Biochim. Biophys. Acta 1834, 1750-1756.
  • Ascenzi, P., Leboffe, L., Polticelli, F. (2013) Reactivity of the human hemoglobin "dark side". IUBMB Life, 65, 121-126.
  • Cervelli, M., Polticelli, F., Fiorucci, L., Angelucci, E., Federico, R., Mariottini, P. (2013) Inhibition of acetylpolyamine and spermine oxidases by the polyamine analogue chlorhexidine. J. Enz. Inhib. & Med. Chem. 28, 463-467.

2012

  • Ascenzi, P., Leboffe, L., Polticelli, F. (2012) Cyanide binding to human plasma heme-hemopexin: a comparative study. Biochem Biophys Res Commun., 428, 239-244.
  • Polticelli, F., Caprari, S., Gianni, S., Ascenzi, P. (2012) GA/GB fold switching may modulate fatty acid transfer from human serum albumin to bacteria. IUBMB Life, 64, 885-888.
  • Polticelli, F., Salvi, D., Mariottini, P., Amendola, R., Cervelli, M. (2012) Molecular evolution of the polyamine oxidase gene family in Metazoa. BMC Evolutionary Biology, 12, 90.
  • Spiezia, M.C., Chiarabelli, C., Polticelli, F. (2012) Recombinant expression and insecticidal properties of a Conus ventricosus conotoxin-GST fusion protein. Toxicon, 60, 744-751.
  • Patriarca, A., Polticelli, F., Piro, M.C., Sinibaldi, F., Mei, G., Bari, M., Santucci, R., Fiorucci, L. (2012) Conversion of cytochrome c into a peroxidase: inhibitory mechanisms and implication for neurodegenerative diseases. Arch. Biochem. Biophys., 522, 62-69.
  • De Lucrezia, D., Slanzi, D., Poli, I., Polticelli, F., Minervini, G. (2012) Do natural proteins differ from random sequences polypeptides? Natural vs. Random proteins classification using an evolutionary Neural Network. PLoS ONE, 7, e36634.
  • Barba, M., Sobolev, A.P., Zobnina, V., Bonaccorsi di Patti, M.C., Cervoni, L., Spiezia, M.C., Schinin�, M.E., Pietraforte, D., Mannina, L., Musci, G., Polticelli, F. (2012) Cupricyclins, Novel Redox-Active Metallopeptides Based on Conotoxins Scaffold. PLoS One, 7, e30739.
  • Leone, S., Basso, E., Polticelli, F., Cozzi, R. (2012) Resveratrol acts as a Topoisomerase II poison in human glioma cells. Int. J. Cancer. 131, E173-178.
  • Toti, D., Atzeni, P., Polticelli, F. (2012) Automatic protein abbreviations discovery and resolution from full-text scientific papers: the PRAISED framework. Bio-Algorithms and Medical-Systems. 8, 13-52.
  • Cervelli, M., Amendola, R., Polticelli, F., Mariottini, P. (2012) Spermine oxidase: ten years after. Amino Acids. 42, 441-450.

2011

  • Evangelista, G., Minervini, G., Polticelli, F., Malawski, M., Szepieniec, T., Flis, L., Prymula, K., Kochanczyk, M., Matczynska, E., Wisniowski, Z., Salapa, K., Banach, M., Roterman, I. (2011) Ab Initio protein structure prediction - The hydrophobicity distribution analysis. Bio-Algorithms and Med-Systems, 7, 5-12.
  • Mangino, G., Percario, Z.A., Fiorucci, G., Vaccari, G., Acconcia, F., Chiarabelli, C., Leone, S., Noto, A., Horenkamp, F.A., Manrique, S., Romeo, G., Polticelli, F., Geyer, M., Affabris, E. (2011) HIV-1 Nef Induces Proinflammatory State in Macrophages through Its Acidic Cluster Domain: Involvement of TNF Alpha Receptor Associated Factor 2. PLoS One 6, e22982.
  • Sinibaldi, F., Droghetti, E., Polticelli, F., Piro, M.C., Di Pierro, D., Ferri, T., Smulevich, G., Santucci, R. (2011) The effects of ATP and sodium chloride on the cytochrome c-cardiolipin interaction: The contrasting behaviour of the horse heart and yeast proteins. J. Inorg. Biochem., 105, 1365-1372.
  • Fiorillo, A., Federico, R., Polticelli, F., Boffi, A., Mazzei, F., Di Fusco, M., Ilari, A., Tavladoraki, P. (2011) The structure of maize polyamine oxidase K300M mutant in complex with the natural substrates provides a snapshot of the catalytic mechanism of polyamine oxidation. FEBS J., 278, 809-821.
  • Ascenzi, P., Polticelli, F., Marino, M., Santucci, R., Coletta, M. (2011) Cardiolipin drives cytochrome c proapoptotic and antiapoptotic actions. IUBMB Life 63,160-165.
  • Marino, M., di Masi, A., Trezza, V., Pallottini, V., Polticelli, F., Ascenzi, P. (2011) Xenosensors car and pxr at work: impact on statin metabolism. Curr. Drug Metab., 12, 300-311.
  • Tavladoraki, P., Cervelli, M., Antonangeli, F., Minervini, G., Stano, P., Federico, R., Mariottini, P., Polticelli, F. (2011) Probing mammalian spermine oxidase enzyme-substrate complex through molecular modeling, site-directed mutagenesis and biochemical characterization. Amino Acids, 40, 1115-1126.
  • Rea, G., Lambreva, M., Polticelli, F., Bertalan, I., Antonacci, A., Pastorelli, S., Damasso, M., Johanningmeier, U., Giardi, M.T. (2011a) Directed Evolution and In Silico Analysis of Reaction Centre Proteins Reveal Molecular Signatures of Photosynthesis Adaptation to Radiation Pressure. PLoS One, 6, e16216.
  • Rea, G., Polticelli, F., Antonacci, A., Lambreva, M., Pastorelli, S., Scognamiglio, V., Zobnina, V., Giardi, M.T. (2011b) Computational biology, protein engineering, and biosensor technology: a close cooperation for herbicides monitoring. In "Herbicides, Theory and Applications", INTECH Publishing, ISBN ISBN 978-953-307-975-2.